VILDO
METFORMIN 500MG + VILDAGLIPTIN 50MG TABLET
Versatile combination to treat type 2 diabetes.
Metformin : Metformin is used to treat high blood sugar levels that are caused by a type of diabetes mellitus or sugar diabetes called type 2 diabetes. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. Using metformin alone, with Vildagliptin will help to lower blood sugar when it is too high and help restore the way you use food to make energy.
Metformin : Metformin is used to treat high blood sugar levels that are caused by a type of diabetes mellitus or sugar diabetes called type 2 diabetes. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. Using metformin alone, with Vildagliptin will help to lower blood sugar when it is too high and help restore the way you use food to make energy.
- It Reduce the amount of glucose produced by the liver.
- Preserves the function of the cells in the pancreas.
- Provides weight stabilization or reduction.
- Lowering the incensement of plasma insulin concentration.
- As per some latest studies, Metformin have so many benefits for our body.
VILDAGLIPTIN
Vildagliptin effectively improves glycemic control, preserves both the α- and β-cell function, and reduces lipotoxicity and insulin resistance. This drug is well tolerated and is weight neutral.
Vildagliptin works in part by increasing the amount of insulin produced by your body. It also reduces the amount of a substance called glucagon being produced by your pancreas. Glucagon causes your liver to produce more sugar, so by reducing the amount of glucagon in your body, this also helps to reduce the levels of sugar in your blood.
Vildagliptin results in reductions in HbA1c Levels of 6 to 12 mmol/mol.( millimoles per mole).
Vildagliptin is an option for a second line pharmacological treatment, for patients who have not achieved sufficient lowering of HbA1c.
Vildagliptin does not cause weight gain and has less risk of hypoglycemia than sulphonylurea medicines.
Vildagliptin works in part by increasing the amount of insulin produced by your body. It also reduces the amount of a substance called glucagon being produced by your pancreas. Glucagon causes your liver to produce more sugar, so by reducing the amount of glucagon in your body, this also helps to reduce the levels of sugar in your blood.
Vildagliptin results in reductions in HbA1c Levels of 6 to 12 mmol/mol.( millimoles per mole).
Vildagliptin is an option for a second line pharmacological treatment, for patients who have not achieved sufficient lowering of HbA1c.
Vildagliptin does not cause weight gain and has less risk of hypoglycemia than sulphonylurea medicines.
IMPROVES LIPID PROFILE OF BODY BY REDUCING HYPER TRIGLYCERIDEMIA.
| Comparison of VILDO with other molecules | Vildagliptin | Sitagliptin | Teneligliptin |
| In vitro selectivity for DPP-4 vs. DPP-4 family members | High | Low | Moderate |
| Half life | High | Moderate | Moderate |
| Hba1c Lowering safety & tolerability profile | Good | Moderate | Moderate |
| Potential for drug interaction | Low | Low | Moderate |
| Food effect | With or after meals also | Before meals | Before meals |
| Weight gain | No | Yes | Yes |
