KONAXICLAV-1.2 INJECTION
AMOXICILLIN SODIUM CLAVULANATE POTASSIUM INJECTION BP
Amoxicillin Sodium belongs to the group of medicines known as penicillin antibiotics. Potassium Clavulanate is a semisynthetic beta-lactamase inhibitor isolated from Streptomyces. The chemical name for Amoxicillin Sodium is sodium; (2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl) acetyl ] amino ] -3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo [3.2.0] heptane-2-carboxylate, its molecular formula is C16H18N3NaO5S; its molecular weight is 387.386 g/mol. The chemical name for Potassium Clavulanate is Potassium; (2R, 3Z, 5R) -3- (2-hydroxyethylidene) 7 – oxo -4 -oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate, its molecular formula is C8H8KNO5; its molecular weight is 237.252 g/mol.
THE CHEMICAL STRUCTURE OF AMOXICILLIN SODIUM AND POTASSIUM CLAVULANATE IS AS FOLLOWS:
COMPOSITION
- Each vial contains:
- Amoxicillin Sodium BP
- Eq. to Amoxicillin 1000 mg
- Potassium Clavulanate BP
- Eq. to Clavulanic Acid 200 mg
INDICATIONS
- KONAXICLAV-1.2 INJECTION is indicated for the treatment of the following infections in adults and children:
- Severe infections of the ear, nose and throat (such as mastoiditis, peritonsillar infections, epiglottitis and sinusitis when accompanied by severe systemic signs and symptoms)
- Acute exacerbations of chronic bronchitis (adequately diagnosed)
- Community acquired pneumonia
- Cystitis
- Pyelonephritis
- Skin and soft tissue infections in particular cellulitis, animal bites, severe dental abscess with spreading cellulitis.
- Bone and joint infections, in particular osteomyelitis
- Intra-abdominal infections
- Femal genital infections
PROPHYLAXIS AGAINST INFECTIONS ASSOCIATED WITH MAJOR SURGICAL PROCEDURES IN ADULTS
- Gastrointestinal tract
- Pelvic cavity
- Head and neck
- Biliary tract surgery
- Consideration should be given to the official guidance on the appropriate use of antibacterial agents.
STORAGE
- Store below 25°C in a dry place in original package.
- Do not use later than the date of expiry.
- KEEP OUT OF REACH OF CHILDREN.
- PRESENTATION : Monopack of 1 vial
- SHELF-LIFE : 24 MONTHS
