CUREXA TABLETS
ARTEMETHER LUMEFANTRINE TABLETS
DESCRIPTION
Artemether & Lumefantrine tablets is a fixed-dose combination tablet of artemether and lumefantrine. Artemether is a methyl ether derivative of dihydroartemisinin, derived from artemisinin. Lumefantrine is a racemic 2, 4, 7, 9-substituted fluorine derivative that conforms structurally, physicochemically and in mode of action to the arylamino alcohol group of antimalarials that includes quinine and mefloquine.
The Chemical Structure for Artemether and Lumefantrine is as follows:
COMPOSITION
Each uncoated tablet contains:-
| Artemether | 80 mg |
| Lumefantrine | 480 mg |
| Excipients | q.s |
INDICATIONS
Artemether & Lumefantrine tablets are indicated for treatment of acute, uncomplicated malaria infections due to Plasmodium falciparum in patients of 5 kg bodyweight and above. Artemether & Lumefantrine tablets have been shown to be effective in geographical regions where resistance to chloroquine has been reported.
LIMITATIONS OF USE
Artemether & Lumefantrine tablets are not approved for patients with severe or complicated P. falciparum malaria.
CONTRAINDICATIONS
Artemether & Lumefantrine tablets are contraindicated in persons with a history of hypersensitivity associated with the use of artemether, lumefantrine, or to any of the excipients of Artemether & Lumefantrine tablets.
STORAGE : Store in an airtight container, protected from light.
PRESENTATION : 1×6 Tablets in one blister in a monopack.
PRESENTATION : 1×6 Tablets in one blister in a monopack.
